California confirms its first case of a double mutant strain which combines mutations from the South African and West Coast variants. The new variant has two mutations, including one found in the California strain, in the spiky protein that the virus latches onto, according to Stanford Health Care spokesperson Lisa Kim. The double mutant that India is talking about is a variant that has 15 different mutations. Double Mutant Coronavirus Variant … Scientists have spotted a new variant with two worrisome mutations in California and India. The variant is also present in other states, but its prevalence among more than 2000 samples collected in California swelled from 0% to greater than … The California Department of Public Health has recorded more than 9,000 cases of the California variant and 851 of the U.K. variant. Researchers at Cedars-Sinai Medical Center (CSMC) in Los Angeles analyzed COVID-19 strains before and after the surge in cases in southern California in October 2020. The California variant has three mutations in the spike protein of SARS-CoV-2, which signals that it may be more infectious than the initial, dominant novel coronavirus strain, the … The D614G variant appears as part of a set of four linked mutations that appear to have arisen once and then moved together around the world as a consistent set of variations. A novel variant of SARS-CoV-2, CAL.20C, was identified, which emerged in Southern California contemporaneously with the local surge in cases. The B.1.1.7 strain of SARS-CoV-2 is a version of the virus with 23 mutations, ... coming from at least 14 states, including California, Florida, New York and Texas. Many of the mutations that make those variants more dangerous are found in the spike protein, and help the virus spread faster and avoid the immune system. The California variant is actually a pair of closely related fellow travelers known as B.1.427 and B.1.429. A new SARS-CoV-2 variant, CAL.20C, has been detected in southern California amid a surge in local infections and is spreading through and beyond the United States, according to a research letter published yesterday in JAMA.. This variant has eight mutations that change amino acids in the spike protein. There's no indication yet this variant can evade vaccines. The researchers also analyzed mutations that have arisen in variants of concern, such as the B.1.1.7 strain from England, the P.1 strain from Brazil, and the B.1.351 strain from South Africa. There have been 35 cases of the Brazilian P.1 variant, 33 cases of the New York B.1.526 variant, 22 cases of the Brazilian P.2 variant and 10 cases of the South African variant. Unlike clade 20G, currently the largest reported clade in North America, this strain is defined by 3 mutations in the S protein characterizing it as a subclade of 20C. Among these mutations is N501Y, which helps the spike latch on more tightly to human cells. The SARS-CoV-2 virus has a low mutation rate overall (much lower than the viruses that cause influenza and HIV-AIDS).
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